Expression levels of 10 candidate genes in lung tissue of vaccinated and TB-infected cynomolgus macaques.

Journal of medical primatology

PubMedID: 23802315

Roodgar M, Lackner A, Kaushal D, Sankaran S, Dandekar S, Trask JS, Drake C, Smith DG. Expression levels of 10 candidate genes in lung tissue of vaccinated and TB-infected cynomolgus macaques. J Med Primatol. 2013;42(3):161-4.
The expression of ten tuberculosis candidate genes in lung and lymph nodes of cynomolgus macaques vaccinated and experimentally infected with Mycobacterium tuberculosis (Mtb) was quantified. The expression of TNFa, IL10, IL1ß, TLR4, IL17, IL6, IL12, and iNOS in the lungs of vaccinated animals was higher than that of non-vaccinated animals.