Polyclonal gammopathy related to renal bleeding in a peritoneal dialysis patient.

Inflammation & allergy drug targets

PubMedID: 23908671

Cho EM, Moon HH, Hwang YJ, Lee SJ, Ko CW, Cho MH. Polyclonal gammopathy related to renal bleeding in a peritoneal dialysis patient. Inflamm Allergy Drug Targets. 2013;56(7):304-7.
Polyclonal gammopathy represents the diffuse activation of B cells and is usually related to inflammation or immune-related diseases. However, the mechanisms leading to polyclonal gammopathy are essentially speculative. Generally, infectious, inflammatory, or various other reactive processes may be indicated by the presence of a broad-based peak or band in the gamma region on serum protein electrophoresis results. A 15-year-old girl, who had been receiving peritoneal dialysis, presented with polyclonal gammopathy and massive gross hematuria. Renal artery embolization was performed, after which the continuous bleeding subsided and albumin-globulin dissociation resolved. This is a rare case of polyclonal gammopathy related to renal bleeding.