With a little help from their friends: interleukin-21, T cells, and B cells.

Immunity

PubMedID: 18631451

Silver JS, Hunter CA. With a little help from their friends: interleukin-21, T cells, and B cells. Immunity. 2008;29(1):7-9.
T follicular cells help B cells generate high-affinity antibodies. Two papers in this issue of Immunity (Nurieva et al., 2008, and Vogelzang et al., 2008) have identified a role for interleukin-21 in the development of these specialized cells and highlight questions about how this dedicated population is generated.