[Cognitive function in eating disorders and therapeutic approach].

Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica

PubMedID: 20976966

Okamoto Y, Miyake Y, Shirao N, Okamoto Y, Yamawaki S. [Cognitive function in eating disorders and therapeutic approach]. Seishin Shinkeigaku Zasshi. 2010;112(8):741-9.
We examined brain activation in the presence of eating disorders while processing unpleasant words concerning body images using functional magnetic resonance imaging (fMRI). Anorexia nervosa restricting type (AN-R) and anorexia nervosa binge-eating/ purging type (AN-BP) patients showed significant amygdala activation. Farther, AN-BP and bulimia nervosa (BN) patients showed significant medial prefrontal cortex activation. Next, we conducted short-term integrated group therapy for eating disorders. After treatment, depressive scores of POMS and emotional-oriented coping scores of CISS were significantly decreased, and EAT scores and self-esteem scores of RSES were significantly increased.