Fossils as candidate material for orthopedic applications.

Journal of biomaterials applications

PubMedID: 20089607

Pesenti H, Leoni M, Motta A, Scardi P. Fossils as candidate material for orthopedic applications. J Biomater Appl. 2011;25(5):445-67.
Ceramic powders from fossil deposits were thoroughly characterized from the material point of view and sintered to produce massive components. The raw material, a mixture of apatite minerals, feldspars, and quartz, seems ideally suitable to obtain a biologically compatible glass ceramic. Preliminary in vitro tests of proliferation and adhesion of MG63 human osteoblast-like cell line on a selected sample are encouraging. Results are correlated with sintering conditions and phase composition: the fossil can be sintered to almost full density at temperatures as low as 900 °C and seems to quickly promote cell activation with respect to hydroxylapatite.