Functional cationic nanomagnet-porphyrin hybrids for the photoinactivation of microorganisms.

ACS nano

PubMedID: 21090642

Carvalho CM, Alves E, Costa L, Tomé JP, Faustino MA, Neves MG, Tomé AC, Cavaleiro JA, Almeida A, Cunha A, Lin Z, Rocha J. Functional cationic nanomagnet-porphyrin hybrids for the photoinactivation of microorganisms. ACS Nano. 2010;4(12):7133-40.
Cationic nanomagnet-porphyrin hybrids were synthesized and their photodynamic therapy capabilities were investigated against the Gram (-) Escherichia coli bacteria, the Gram (+) Enterococcus faecalis bacteria and T4-like phage. The synthesis, structural characterization, photophysical properties, and antimicrobial activity of these new materials are discussed. The results show that these new multicharged nanomagnet-porphyrin hybrids are very stable in water and highly effective in the photoinactivation of bacteria and phages. Their remarkable antimicrobial activity, associated with their easy recovery, just by applying a magnetic field, makes these materials novel photosensitizers for water or wastewater disinfection.