The use of lymecycline and benzoyl peroxide for the treatment of progressive macular hypomelanosis: a prospective study.

Anais brasileiros de dermatologia

PubMedID: 21987158

Cavalcanti SM, Querino MC, Magalhães V, França ER, Magalhães M, Alencar E. The use of lymecycline and benzoyl peroxide for the treatment of progressive macular hypomelanosis: a prospective study. An Bras Dermatol. 2011;86(4):813-4.
Progressive macular hypomelanosis is a dermatosis of uncertain etiology. The participation of Propionibacterium acnes has been suggested in view of the response achieved following therapy with drugs that are active against this bacterium. This report describes a series of thirteen patients with progressive macular hypomelanosis who were treated with an association of lymecycline and benzoyl peroxide over a three-month period. Response to treatment was excellent and the positive results were maintained during the entire follow up period.