Familial progressive hypo- and hyperpigmentation: a variant case.

Indian journal of dermatology, venereology and leprology

PubMedID: 22565436

Zhang RZ, Zhu WY. Familial progressive hypo- and hyperpigmentation: a variant case. Indian J Dermatol Venereol Leprol. 2012;78(3):350-3.
Familial progressive hyper- and hypopigmentation (FPHH) is characterized by diffuse hyperpigmentation with variable intensity. Cafe'-au-lait macules and larger hypopigmented ash-leaf macules are also present. Herein, we reported a variant case of FPHH. The patient was a two-year-old Chinese girl showing diffuse hyper- and hypopigmented lesions, longitudinal melanonychia in both thumbs, and infantile seizures, without any lentigines.