Phylogenetic analysis of a near-full-length sequence of an erythrovirus genotype 3 strain isolated in Brazil.

Archives of virology

PubMedID: 19701602

Keller LW, Barbosa ML, Melo FL, Pereira LM, David-Neto E, Lanhez LE, Durigon EL. Phylogenetic analysis of a near-full-length sequence of an erythrovirus genotype 3 strain isolated in Brazil. Arch Virol. 2009;154(10):1685-7.
Human parvovirus B19 is the only member of the genus Erythrovirus that causes human disease. Recent findings of several strains with considerable sequence divergence from B19 have suggested a new classification for parvovirus genotypes as 1 (B19), 2 (A-6 and LaLi) and 3 (V9). In their overall DNA sequence, the three genotypes differ by approximately 10%. Here, we report the isolation of a genotype-3-related strain named BR543 during a prospective study conducted in Sao Paulo, Brazil. Analysis of the nearly full-length genome sequence of BR543 indicates that this B19 variant sequence clusters with Gh2768, a strain from Ghana belonging to subtype 3b, and showed mostly synonymous substitutions.