Perylene derivatives produced by Alternaria alternata, an endophytic fungus isolated from Laurencia species.

Natural product communications

PubMedID: 19967977

Gao SS, Li XM, Wang BG. Perylene derivatives produced by Alternaria alternata, an endophytic fungus isolated from Laurencia species. Nat Prod Commun. 2009;4(11):1477-80.
Two new perylene derivatives, 7-epi-8-hydroxyaltertoxin I (1) and 6-epi-stemphytriol (2), along with two known compounds stemphyperylenol (3) and altertoxin I (4) were isolated from Alternaria alternata, a marine endophytic fungus derived from an unidentified algal species of the genus Laurencia. Structures of compounds 1-4 were determined on the basis of detailed spectroscopic analysis, as well as by comparison with literature reports. The antimicrobial activities of compounds 1 and 3 against Staphylococcus aureus, Escherichia coli, and Aspergillus niger were evaluated; neither showed obvious activity.