Crystal structures, DNA-binding studies and antioxidant activities of the Ln(III) complexes with 7-methoxychromone- 3-carbaldehyde-isonicotinoyl hydrazone.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

PubMedID: 19404747

Wang Q, Yang ZY, Qi GF, Qin DD. Crystal structures, DNA-binding studies and antioxidant activities of the Ln(III) complexes with 7-methoxychromone- 3-carbaldehyde-isonicotinoyl hydrazone. Biometals. 2009;22(6):927-40.
The neutral mononuclear Ln(III) complexes (Ln = La, Sm) with 7-methoxychrom-one-3-carbaldehyde-isonicotinoyl hydrazone ligand (L) have been synthesized, characterized and investigated their interactions with calf-thymus DNA. The results show that the binding affinity of the La(III) complex is stronger than that of the Sm(III) complex and that of the ligand (L). Furthermore, the antioxidant activities of the ligand (L) and its Ln(III) complexes (Ln = La, Sm) were studied in detail.