Application of mid-infrared molecular spectroscopy for assessment of biochemical parameters of blood serum.

Bulletin of experimental biology and medicine

PubMedID: 21116513

Khaustova SA, Davydov II, Trushkin EV, Shkurnikov MU, Mueller R, Backhaus J, Tonevitsky AG. Application of mid-infrared molecular spectroscopy for assessment of biochemical parameters of blood serum. Bull Exp Biol Med. 2009;148(6):943-7.
The method of mid-infrared molecular spectroscopy allows precise measuring of the concentrations of a large number of biological molecules in a minimal sample volume. Method of projections on latent structures was used for plotting the calibration models. On the basis on mid-infrared spectral data we obtained calibration models for calculation of serum content of various substances: albumin, cholesterol, glucose, total protein, urea, 70 Da heat shock protein, and malonic dialdehyde.