[Health-related quality of life in patients with chronic kidney disease].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia

PubMedID: 19048570

Procaccini DA, Angelini P, Aucella F, Avanzi C, Brusasco S, Carta G, Cataldi G, Cogoni G, D'Agostino F, d'Elia F, Del Mastro G, Dell'aquila R, De Min AM, Feliciangeli G, Freddi P, Gallucci M, Giannico G, Gigante B, Infante B, Ktena M, Manno C, Marseglia CD, Navarra A, Pappani A, Pompa G, Querques M, Russo D, Sacchetti A, Sechi MA, Specchio A, Stallone C, Virgilio M, Apulia Nephrology Quality Of Life Study. [Health-related quality of life in patients with chronic kidney disease]. G Ital Nefrol. 2008;25(6):694-701.
Assessment of quality of life in patients with different degrees of chronic kidney disease is an important issue because of its impact on clinical decisions and financial resource management in the health-care system. The aim of this study was to assess whether a generic instrument like the SF-36 questionnaire is able to discriminate three different populations of patients with different degrees of renal disease (pre-ESRD, ESRD, TxR). Five hundred sixty-three patients from 12 Italian nephrology units completed the SF-36 scales by themselves. The results from these samples were compared with those from the general population. Univariate analysis and multivariate regression were used. The generic SF-36 questionnaire proved to be a powerful instrument to discriminate populations with different degrees of chronic renal failure. The quality of life of patients on dialysis is significantly worse than that of the normal population and other patients with less severe renal function impairment.