Clopidogrel-associated acute migratory arthritis following kidney-pancreas transplantation.

International journal of immunopathology and pharmacology

PubMedID: 16831311

Muthusamy AS, Vaidya A, Friend PJ. Clopidogrel-associated acute migratory arthritis following kidney-pancreas transplantation. Int J Immunopathol Pharmacol. 2006;19(2):443-4.
Clopidogrel is a potent inhibitor of platelet aggregation and has been used as an alternative, or as an adjunct to aspirin in reducing the risk of thrombosis. A 34-year-old uremic type 1 male diabetic patient who underwent simultaneous kidney-pancreas transplantation was given clopidogrel as he was allergic to aspirin. He developed polyarthralgia one week later, followed in a few days by symmetrical migratory polyarthritis, which resolved completely on withdrawing the drug. The implications to clinical management in a transplant setting are discussed.