Phenolic constituents of the roots of Sophora flavescens.

Journal of natural products

PubMedID: 16933887

Shen CC, Lin TW, Huang YL, Wan ST, Shien BJ, Chen CC. Phenolic constituents of the roots of Sophora flavescens. J Nat Prod. 2006;69(8):1237-40.
From the roots of Sophora flavescens collected in Taiwan, four new prenylflavonoids, sophoraflavanone K (1), sophoraflavanone L (2), 8-lavandulylkaempferol (3), and cyclokuraridin (4), a new arylbenzofuran, 2-(2,4-dihydroxy-5-prenylphenyl)-5,6-methylenedioxybenzofuran (5), and a new prenyldibenzoyl derivative, sophoradione (6), were isolated. The structures of 1-6 were determined by spectroscopic data analysis. Compounds 2-6 were evaluated for cytotoxic activity against the KB epidermoid carcinoma cell line.