[Eosinophilia in peripheral blood of women with recurrent vaginal candidiasis].

Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia

PubMedID: 24337057

Queiroz Filho J, Gonçalves AK, Cavalcante GB, Pessoa DC, Eleutério J, Giraldo PC, Sales VS. [Eosinophilia in peripheral blood of women with recurrent vaginal candidiasis]. Rev Bras Ginecol Obstet. 2013;35(10):453-7.
PURPOSE
To quantify the number of defense cells and immunoglobulin E (IgE) levels in peripheral blood sampled from women with recurrent vulvovaginal candidiasis.

METHODS
A cross-sectional study was conducted on 60 women, 40 with vulvovaginal candidiasis and 20 controls. The defense cells were identified using an impedance system combined with flow cytometry and total and specific IgE was measured by chemiluminescence. The Mann-Whitney test was used for nominal variables and the Spearman test was used to determine the correlation of IgE concentration and eosinophils in peripheral blood.

RESULTS
The number of eosinophils in peripheral blood from patients with recurrent vulvovaginal candidiasis, 302.60 (±253.07), was significantly higher compared to control, 175.75 (±109.24) (p=0.037). Serum levels of total and specific IgE were similar in the groups of women with and without recurrent vulvovaginal candidiasis (p=0.361). However, there was a moderate positive correlation between eosinophils and total serum IgE in the candidiasis group (r=0.25).

CONCLUSION
Women with recurrent vulvovaginal candidiasis are more likely to have eosinophils in peripheral blood.