[Successful multidisciplinary treatment of a case of lymph node recurrence with invasion to adjacent organs after curative resection of esophageal cancer].

Gan to kagaku ryoho. Cancer & chemotherapy

PubMedID: 24394031

Murakami K, Miyata H, Yamasaki M, Miyazaki Y, Takahashi T, Kurokawa Y, Takiguchi S, Nakajima K, Mori M, Doki Y. [Successful multidisciplinary treatment of a case of lymph node recurrence with invasion to adjacent organs after curative resection of esophageal cancer]. Gan To Kagaku Ryoho. 2013;40(12):2115-7.
In the present report, we describe a case of a woman who underwent esophagectomy for esophageal carcinosarcoma in October 2008. Computed tomography (CT) and endoscopy indicated lymph node recurrence with invasion into adjacent organs and oropharyngeal carcinoma in September 2009. She subsequently received 2 courses of chemotherapy (5-fluorouracil+ cisplatin+adriamycin) plus radiotherapy with a total dose of 60 Gy. Although a partial response was achieved after this treatment, CT still indicated the presence of residual lesions. Therefore, surgical excision was performed at the site of the lymph node recurrence and for oropharyngeal carcinoma. Thus, we performed a radical operation by resecting the skin, sternum, clavicle, ribs, innominate vein, bronchus, oropharyngeal, larynx, and lymph node; transplanted a free thigh flap; and performed a mediastinal tracheostomy. She has been alive without recurrence for 3 years and 4 months after the operation.