[Effect of trigeminus nerve on facialis-denervated facial muscle atrophy].

Sheng li xue bao : [Acta physiologica Sinica]

PubMedID: 11973584

Luo QF, Li XE, Gong ZX. [Effect of trigeminus nerve on facialis-denervated facial muscle atrophy]. Sheng Li Xue Bao. 2002;54(2):94-8.
In the present study we made out an animal model on rabbit whose trigeminus and facialis nerves were simultaneously or only the latter one was severed. The pathological changes in facial muscle atrophy under different nerve injuries were investigated. The degeneration of contractile proteins of upper lip muscle -- myosin and actin was observed. In addition, we also examined the ultrastructural changes in the muscle atrophy in the two above-mentioned nerve injury cases. We observed that the intact trigeminus nerve could delay and lighten the atrophy of facialis-denervated facial muscle and attenuate the degeneration of myosin and actin, as well as decrease the increment of collagen and maintain the ultrastructure of the thick and thin muscle filaments. These results may provide the possibility of improvement of clinical treatment for facial muscle palsy.