Response to therapy following retreatment of serofast early syphilis patients with benzathine penicillin.

Clinical Infectious Diseases

PubMedID: 23118269

Seña AC, Wolff M, Behets F, Van Damme K, Martin DH, Leone P, McNeil L, Hook EW. Response to therapy following retreatment of serofast early syphilis patients with benzathine penicillin. Clin Infect Dis. 2013;56(3):420-2.
Persistent nontreponemal titers after treatment are common among patients with early syphilis. We retreated 82 human immunodeficiency virus-negative early syphilis participants who were serofast at 6 months using benzathine penicillin. Only 27% exhibited serological response after retreatment and after an additional 6 months of follow-up.