Management of neck metastases in T2N0 lip squamous cell carcinoma.

American Journal of Otolaryngology

PubMedID: 23164629

Vanderlei JP, Pereira-Filho FJ, da Cruz FA, de Mello FL, Kruschewsky Lde S, de Freitas LC, de Mello-Filho FV. Management of neck metastases in T2N0 lip squamous cell carcinoma. Am J Otolaryngol. 2013;34(2):103-6.
BACKGROUND
Prophylactic neck dissection (PND) is indicated when the chance of occult lymph node metastases from head and neck tumors is significant. There is no consensus regarding which tumor size PND would be indicated in cases of lip cancer.

METHODS
A total of 139 patients with surgically treated lip cancer were selected. The size of the lesion (T) and the presence of lymph node metastases (N) were assessed by examining the medical records. For analysis purposes, the T2 group was divided into T2a (2 to 3 cm) and T2b (3 to 4 cm).

RESULTS
The following distribution of incidence of neck metastases was observed in the study groups: 11.7% in T1, 9% in T2a, 43.7% in T2b, and 52.2% in T3+T4. Statistical comparison of the groups (p) revealed the following results: T2aXT2b=0.03; T2aXT3+T4=0.001.

CONCLUSION
PND is indicated for tumors larger than 3 cm.