Cervical spondylodiscitis - A clinical analysis of surgically treated patients and review of the literature.

Clinical neurology and neurosurgery

PubMedID: 24438811

Ozkan N, Wrede K, Ardeshiri A, Hagel V, Dammann P, Ringelstein A, Sure U, Erol Sandalcioglu I. Cervical spondylodiscitis - A clinical analysis of surgically treated patients and review of the literature. Clin Neurol Neurosurg. 2014;117C86-92.
OBJECTIVE
The aim of this study was to analyze our clinical and neurological results of surgically treated patients suffering from cervical spondylodiscitis with focusing particularly on the surgical methods used and to review the literature.

PATIENTS AND METHODS
We present a series of 21 patients operated with cervical spondylodiscitis between 1998 and 2011. Basic demographic data, comorbidities, the radiological segments involved, the surgical strategy with special consideration of the material used and the clinical outcome were evaluated retrospectively.

RESULTS
The mean age of 6 female and 12 male patients was 65 years (range 28-89 years). The mean follow-up was 3.7 years ranging between 4 weeks and 9 years. The leading symptom was neurological deficits rather than pain. The segments C 5/6 (n=8) and C 6/7 (n=7) were most frequently involved. Different surgical methods depending on the location, anatomical and pathological condition and extension of the lesion were performed.

CONCLUSION
In conclusion, cervical spondylodiscitis could effectively be treated in the presented patient cohort by surgical decompression, debridement and PMMA or bone graft implants followed by long term antibiotic therapy. The presented surgical reconstruction technique with PMMA might be a feasible alternative to the use of bone graft or cages. The promising clinical results warrant future prospective studies to further investigate this technique.