A study of the predisposition of Schistosomiasis mansoni to pyogenic liver abscess in experimentally infected mice.

Journal of the Egyptian Society of Parasitology

PubMedID: 10786038

Mahmoud MS, Awad AA. A study of the predisposition of Schistosomiasis mansoni to pyogenic liver abscess in experimentally infected mice. J Egypt Soc Parasitol. 2000;30(1):277-86.
In murine experimental model, the present work was carried out to study the possible predisposition of S. mansoni infection to pyogenic liver abscess, through a concurrent infection with Staphylococcus aureus. Pyogenic liver abscesses containing the bacterial organism were found in 85% of mice infected with concurrent early S. mansoni infection and S. aureus, in 35% of mice with late S. mansoni infection and the bacterial infection, and in 60% of mice with concurrent immunosuppressed late St. mansoni infection and staphylococcal infection. The early S. mansoni infection, immunosuppressed late schistosomiasis mansoni, and to a less extant late schistosomiasis mansoni, with concurrent bacterial infections can predispose to pyogenic liver abscess which has implicative effect on clinical cases.